The Florida Surgeon General, Dr. Joseph Ladapo, has called for a halt to the use of all mRNA COVID-19 vaccines on the market. This comes after the FDA responded to Dr. Ladapo and did not alleviate his concerns regarding DNA integration. The call to halt administration comes less than two weeks after Del Bigtree interviewed Dr. Ladapo regarding his concerns with the human genome.
“With these mRNA vaccines, you’ve basically got a passport into human cells,” Dr. Ladapo stated on The HighWire. “So, whereas in the past, DNA would have a hard time ever getting into a cell, let alone getting into the nucleus of the cell, now you have these lipid nanoparticles that everyone is very excited about with the mRNA vaccines, that they carry mRNA in, but they almost certainly also carry DNA into the cells. So, it completely changes the risk analysis. And this risk, however low it may be, is one that the FDA has acknowledged in the past, and somehow they think that they can get away with not assessing this time, and it’s totally not gonna happen.”
Specifically, Dr. Ladapo points out three main concerns that come right from the FDA’s regulatory guidance regarding DNA vaccines in 2007.
From the guidance:
DNA integration could theoretically impact a human’s oncogenes, the genes that can transform a healthy cell into a cancerous one. DNA integration may result in chromosomal instability. The Guidance for Industry discusses the biodistribution of DNA vaccines and how such integration could affect unintended parts of the body, including blood, heart, brain, liver, kidney, bone marrow, ovaries/testes, lung, draining lymph nodes, spleen, the site of administration and subcutis at the injection site.
The FDA letter response dismisses the 2007 guidance document as irrelevant to the mRNA vaccines. Peter Marks, in the letter, states that the document was developed for DNA vaccines, not for DNA contaminants in other types of vaccines. For this reason, according to Marks, this document does not apply to mRNA vaccines. Marks points to animal studies as evidence that there is no genotoxicity from the residual DNA fragments in the mRNA vaccines. Dr. Ladapo insists that this is not the type of study that needs to be performed to ensure the safety of the product.
Dr. Ladapo states, “The FDA’s response does not provide data or evidence that the DNA integration assessments they recommended themselves have been performed. Instead, they pointed to genotoxicity studies – which are inadequate assessments for DNA integration risk. In addition, they obfuscated the difference between the SV40 promoter/enhancer and SV40 proteins, two elements that are distinct.”
The FDA response letter does mention the SV40 protein a few times but never addresses the SV40 promoter/enhancer, as Dr. Ladapo mentioned. The FDA letter states, “it is quite implausible that the residual DNA fragments located in the cytosol could find their way into the nucleus through the nuclear membrane present in intact cells and then be incorporated into chromosomal DNA.”
Dr. Ladapo talked about the notion that the small amounts of residual DNA are not a concern, as has been stated by representatives of the FDA. On the Highwire, he said “Yes, I get it. It’s small amounts of DNA. Let’s make sure that none of those small amounts, which, by the way, are equivalent based on some of the studies that are out there, billions of particles per dose of DNA. Let’s make sure it’s not ending up somewhere, like in eggs or in sperm, in a place that could be heritable, could be passed onto offspring, or could cause other problems. Let’s just make sure out of respect for the human genome.”
Dr. Ladapo went on to point out what the FDA has stated in the past, despite Peter Marks of the FDA dismissing the 2007 guidance document as not being related to mRNA vaccines. Dr. Ladapo is making the point that the due diligence the agency expected for DNA vaccines should also be a requirement for the mRNA technology.
“The issue that the FDA have themselves acknowledged in the past is that we just have to do our due diligence to make sure that when we are using technology that has the potential to introduce DNA into our bloodstreams, which is something that happens with some biological medications and some vaccines, we just have to do our due diligence to make sure that DNA isn’t ending up somewhere we don’t want it to be. The problem here is that due diligence hasn’t been done. The FDA wants you and me to believe that that’s ok. That is not okay. That is so disrespectful to God’s work and creation not to do your due diligence with this type of work.”
The alarm that Dr. Ladapo is raising regarding the potential harms of DNA integration through the lipid nanoparticle mRNA technology can best be understood by what the totality of science knows about human DNA.
“We only know about 1 or 2 percent of what our DNA does,” Dr. Ladapo said. “The rest of it, almost all of our DNA is a complete mystery known only to God. It’s even beyond wreckless what we’re seeing. Unfortunately, it’s not surprising, given the track record they’ve accumulated in COVID.”
The conversation transitioned into predictions and expectations about when people look back at COVID and vaccines in the history books. “There will be a reckoning eventually, and frankly, I think when the real damage has been totally accounted for, I’m not sure we’re even going to have a Pfizer anymore.” One of Dr. Ladapo’s final statements in the interview was in agreement with Del Bigtree. He said, “This is going to go down as a very sad point in history, unfortunately.”