500 Thursdays in a row. Nine years of real news you got nowhere else. This week, The HighWire looks back at the stories and legal fights that shaped its first 500 episodes.

And breaking news: ICAN’s lead attorney, Aaron Siri, Esq., joins Del to discuss an historic legal victory funded by ICAN against a vaccine manufacturer. Who’s the big bad wolf, now?

Plus, our live studio audience is in for a big surprise when two well-known Hollywood rebels join the show. They’ll talk about the fight for freedom that put them at odds with mainstream Hollywood and the new series they’ve joined forces to create, which is already making waves.

Guests: Aaron Siri, Esq., Roseanne Barr, Drea de Matteo

Airdate: October 29, 2026